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Pharmaceutical Grade Steroids Bodybuilding Hormone Supplements Acitretin CAS 55079-83-9

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Pharmaceutical Grade Steroids Bodybuilding Hormone Supplements Acitretin CAS 55079-83-9

Brand Name : DV-Labs
Model Number : 55079-83-9
Certification : GMP
Place of Origin : HONG KONG
MOQ : 50G
Price : Negotiable
Payment Terms : Western Union
Supply Ability : 200kg / month
Delivery Time : Delivery within 24h after payment
Packaging Details : Discreet ways of packing for Customs pass guaranteed
Product Name : Acitretin
Assay : 98%
Quality Standards : USP30
Appearance : Chemical Properties Crystalline Solid
Shipping Out : In 24 Hours After Confirm Payment
Email : Service_TS@126.com
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Purity 98%Raw Steroid Powders Acitretin CAS 55079-83-9 For Bodybuilding


Specifications


Product Name :Acitretin
Synonyms: retinoidetretin,(all-e)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraen;6,8-nonatetraenoicacid,3,7-dimethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-4;all-trans-3,7-dimethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-2,4,6,8-nonatetra;all-trans-etretin;retinoidetretin;ro10-1670;(E)-9-(4-METHOXY-2,3,6-TRIMETHYLPHENYL)-3,7-DIMETHYL-2,4,6,8-NONATETRAENOIC ACID;etretin
CAS: 55079-83-9
MF: C21H26O3
MW: 326.43
EINECS: 259-474-4
mp 228-230°C
storage temp. 2-8°C
Chemical Properties Crystalline Solid
Usage A synthetic retinoid which is the major metabolite of etretinate (E938000).
Purity: 98%


Product Description:


Acitretin (trade names Soriatane and Neotigason) is a second-generation retinoid. It is taken orally, and is typically used forpsoriasis.

It is a metabolite of etretinate, which was used prior to the introduction of acitretin. Etretinate was discontinued because it had a narrow therapeutic index as well as a long elimination half-life(t1/2=120 days), making dosing difficult. In contrast, acitretin's half-life is approximately 2 days. However, because acitretin can be reverse metabolised into etretinate which has an extremely long half-life, women must avoid becoming pregnant for at least 3 years after discontinuing acitretin. Therefore, acitretin is generally not recommended for women of child-bearing age with a risk of becoming pregnant.

Acitretin is an oral retinoid used in the treatment of severe resistant psoriasis. Because of the potential for problems and severe side effects it is generally used in only very severe cases of psoriasis that have been unresponsive to other treatments. It binds to nuclear receptors that regulates gene transcription. They induce keratinocytedifferentiation and reduce epidermal hyperplasia, leading to the slowing of cell reproduction. Acitretin is readily absorbed and widely distributed after oral administration. A therapeutic effect occurs after 2 to 4 weeks or longer.

Patients that have received the medication are advised against giving blood for at least 3 years due to the risk of birth defects.


Applications:


Acitretin (CAS NO.55079-83-9) is a synthetic retinoid which is the major metabolite of etretinate. It is typically used for psoriasis. Acitretin is a metabolite of etretinate, which was used prior to the introduction of acitretin.


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